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Functional heterogeneity of cytotoxic T cells and tumor resistance to cytotoxic hits limit anti‐tumor activity in vivo

Cytotoxic T cells (CTLs) can eliminate tumor cells through the delivery of lethal hits, but the actual efficiency of this process in the tumor microenvironment is unclear. Here, we visualized the capacity of single CTLs to attack tumor cells in vitro and in vivo using genetically encoded reporters t...

詳細記述

保存先:
書誌詳細
出版年:EMBO J
主要な著者: Khazen, Roxana, Cazaux, Marine, Lemaître, Fabrice, Corre, Beatrice, Garcia, Zacarias, Bousso, Philippe
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167356/
https://ncbi.nlm.nih.gov/pubmed/33855732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106658
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