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Human Monoclonal IgM Antibody Promotes CNS Myelin Repair Independent of Fc Function

The human monoclonal IgM antibody sHIgM22 and mouse IgM monoclonal antibody 94.03 bind to oligodendrocytes, induce calcium signals in cultured glial cells, and promote remyelination in mouse models of multiple sclerosis. In order to address the mechanisms employed by these antibodies to promote CNS...

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Bibliografische gegevens
Gepubliceerd in:Brain Pathol
Hoofdauteurs: Ciric, Bogoljub, Howe, Charles L., Soldan, Mateo Paz, Warrington, Arthur E., Bieber, Allan J., Van Keulen, Virginia, Rodriguez, Moses, Pease, Larry R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 2006
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096021/
https://ncbi.nlm.nih.gov/pubmed/14655764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2003.tb00489.x
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