A monoclonal natural human IgM protects axons in the absence of remyelination

BACKGROUND: Whereas demyelination underlies early neurological symptoms in multiple sclerosis (MS), axonal damage is considered critical for permanent chronic deficits. Intracerebral infection of susceptible mouse strains with Theiler’s murine encephalomyelitis virus (TMEV) results in chronic induce...

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Bibliografiset tiedot
Julkaisussa:J Neuroinflammation
Päätekijät: Wootla, Bharath, Denic, Aleksandar, Warrington, Arthur E., Rodriguez, Moses
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2016
Aiheet:
Short Report
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850699/
https://ncbi.nlm.nih.gov/pubmed/27126523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0561-3
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