A monoclonal natural human IgM protects axons in the absence of remyelination

BACKGROUND: Whereas demyelination underlies early neurological symptoms in multiple sclerosis (MS), axonal damage is considered critical for permanent chronic deficits. Intracerebral infection of susceptible mouse strains with Theiler’s murine encephalomyelitis virus (TMEV) results in chronic induce...

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Bibliografske podrobnosti
izdano v:J Neuroinflammation
Main Authors: Wootla, Bharath, Denic, Aleksandar, Warrington, Arthur E., Rodriguez, Moses
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Short Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850699/
https://ncbi.nlm.nih.gov/pubmed/27126523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0561-3
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