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A monoclonal natural human IgM protects axons in the absence of remyelination

BACKGROUND: Whereas demyelination underlies early neurological symptoms in multiple sclerosis (MS), axonal damage is considered critical for permanent chronic deficits. Intracerebral infection of susceptible mouse strains with Theiler’s murine encephalomyelitis virus (TMEV) results in chronic induce...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Wootla, Bharath, Denic, Aleksandar, Warrington, Arthur E., Rodriguez, Moses
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850699/
https://ncbi.nlm.nih.gov/pubmed/27126523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0561-3
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