PDGF is Required for Remyelination-Promoting IgM Stimulation of Oligodendrocyte Progenitor Cell Proliferation

BACKGROUND: Promotion of remyelination is a major goal in treating demyelinating diseases such as multiple sclerosis (MS). The recombinant human monoclonal IgM, rHIgM22, targets myelin and oligodendrocytes (OLs) and promotes remyelination in animal models of MS. It is unclear whether rHIgM22-mediate...

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Detaylı Bibliyografya
Asıl Yazarlar: Watzlawik, Jens O., Warrington, Arthur E., Rodriguez, Moses
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562326/
https://ncbi.nlm.nih.gov/pubmed/23383310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055149
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