Human Monoclonal IgM Antibody Promotes CNS Myelin Repair Independent of Fc Function

The human monoclonal IgM antibody sHIgM22 and mouse IgM monoclonal antibody 94.03 bind to oligodendrocytes, induce calcium signals in cultured glial cells, and promote remyelination in mouse models of multiple sclerosis. In order to address the mechanisms employed by these antibodies to promote CNS...

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Библиографические подробности
Опубликовано в: :Brain Pathol
Главные авторы: Ciric, Bogoljub, Howe, Charles L., Soldan, Mateo Paz, Warrington, Arthur E., Bieber, Allan J., Van Keulen, Virginia, Rodriguez, Moses, Pease, Larry R.
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 2006
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096021/
https://ncbi.nlm.nih.gov/pubmed/14655764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2003.tb00489.x
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