Human Monoclonal IgM Antibody Promotes CNS Myelin Repair Independent of Fc Function

The human monoclonal IgM antibody sHIgM22 and mouse IgM monoclonal antibody 94.03 bind to oligodendrocytes, induce calcium signals in cultured glial cells, and promote remyelination in mouse models of multiple sclerosis. In order to address the mechanisms employed by these antibodies to promote CNS...

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Detalles Bibliográficos
Publicado en:Brain Pathol
Main Authors: Ciric, Bogoljub, Howe, Charles L., Soldan, Mateo Paz, Warrington, Arthur E., Bieber, Allan J., Van Keulen, Virginia, Rodriguez, Moses, Pease, Larry R.
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2006
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096021/
https://ncbi.nlm.nih.gov/pubmed/14655764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2003.tb00489.x
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