Human Monoclonal IgM Antibody Promotes CNS Myelin Repair Independent of Fc Function

The human monoclonal IgM antibody sHIgM22 and mouse IgM monoclonal antibody 94.03 bind to oligodendrocytes, induce calcium signals in cultured glial cells, and promote remyelination in mouse models of multiple sclerosis. In order to address the mechanisms employed by these antibodies to promote CNS...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Brain Pathol
Asıl Yazarlar: Ciric, Bogoljub, Howe, Charles L., Soldan, Mateo Paz, Warrington, Arthur E., Bieber, Allan J., Van Keulen, Virginia, Rodriguez, Moses, Pease, Larry R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 2006
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096021/
https://ncbi.nlm.nih.gov/pubmed/14655764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2003.tb00489.x
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