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Molecular insights into substrate recognition and discrimination by the N-terminal domain of Lon AAA+ protease
The Lon AAA+ protease (LonA) is a ubiquitous ATP-dependent proteolytic machine, which selectively degrades damaged proteins or native proteins carrying exposed motifs (degrons). Here we characterize the structural basis for substrate recognition and discrimination by the N-terminal domain (NTD) of L...
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| 發表在: | eLife |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
eLife Sciences Publications, Ltd
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8087443/ https://ncbi.nlm.nih.gov/pubmed/33929321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64056 |
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