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Distinct quaternary structures of the AAA+ Lon protease control substrate degradation

Lon is an ATPase associated with cellular activities (AAA+) protease that controls cell division in response to stress and also degrades misfolded and damaged proteins. Subunits of Lon are known to assemble into ring-shaped homohexamers that enclose an internal degradation chamber. Here, we demonstr...

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Détails bibliographiques
Auteurs principaux: Vieux, Ellen F., Wohlever, Matthew L., Chen, James Z., Sauer, Robert T., Baker, Tania A.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670373/
https://ncbi.nlm.nih.gov/pubmed/23674680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307066110
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