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Protein unfolding and degradation by the AAA+ Lon protease

AAA+ proteases employ a hexameric ring that harnesses the energy of ATP binding and hydrolysis to unfold native substrates and translocate the unfolded polypeptide into an interior compartment for degradation. What determines the ability of different AAA+ enzymes to unfold and thus degrade different...

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Autori principali: Gur, Eyal, Vishkautzan, Marina, Sauer, Robert T
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley Subscription Services, Inc., A Wiley Company 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324771/
https://ncbi.nlm.nih.gov/pubmed/22162032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2013
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