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Protein unfolding and degradation by the AAA+ Lon protease

AAA+ proteases employ a hexameric ring that harnesses the energy of ATP binding and hydrolysis to unfold native substrates and translocate the unfolded polypeptide into an interior compartment for degradation. What determines the ability of different AAA+ enzymes to unfold and thus degrade different...

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書目詳細資料
Main Authors: Gur, Eyal, Vishkautzan, Marina, Sauer, Robert T
格式: Artigo
語言:Inglês
出版: Wiley Subscription Services, Inc., A Wiley Company 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324771/
https://ncbi.nlm.nih.gov/pubmed/22162032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2013
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