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Recognition of misfolded proteins by Lon, a AAA(+) protease
Proteins unfold constantly in cells, especially under stress conditions. Degradation of denatured polypeptides by Lon and related ATP-dependent AAA(+) proteases helps prevent toxic aggregates formation and other deleterious consequences, but how these destructive enzymatic machines distinguish betwe...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518814/ https://ncbi.nlm.nih.gov/pubmed/18708584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1670908 |
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