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Roles of the N domain of the AAA+ Lon protease in substrate recognition, allosteric regulation, and chaperone activity
Degron binding regulates the activities of the AAA+ Lon protease in addition to targeting proteins for degradation. The sul20 degron from the cell-division inhibitor SulA is shown here to bind to the N domain of E. coli Lon, and the recognition site is identified by crosslinking and scanning for mut...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3877180/ https://ncbi.nlm.nih.gov/pubmed/24205897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12444 |
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