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Assaying the kinetics of protein denaturation catalyzed by AAA+ unfolding machines and proteases
ATP-dependent molecular machines of the AAA+ superfamily unfold or remodel proteins in all cells. For example, AAA+ ClpX and ClpA hexamers collaborate with the self-compartmentalized ClpP peptidase to unfold and degrade specific proteins in bacteria and some eukaryotic organelles. Although degradati...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4418879/ https://ncbi.nlm.nih.gov/pubmed/25870262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505881112 |
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