Loading...

The AAA+ ClpX machine unfolds a keystone subunit to remodel the Mu transpososome

A hyperstable complex of the tetrameric MuA transposase with recombined DNA must be remodeled to allow subsequent DNA replication. ClpX, a AAA+ enzyme, fulfills this function by unfolding one transpososome subunit. Which MuA subunit is extracted, and how complex destabilization relates to establishm...

Full description

Saved in:
Bibliographic Details
Main Authors: Abdelhakim, Aliaa H., Sauer, Robert T., Baker, Tania A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823858/
https://ncbi.nlm.nih.gov/pubmed/20133746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910905106
Tags: Add Tag
No Tags, Be the first to tag this record!