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Unique contacts direct high-priority recognition of the tetrameric transposase-DNA complex by the AAA+ unfoldase ClpX

Clp/Hsp100 ATPases remodel and disassemble multiprotein complexes, yet little is known about how they preferentially recognize these complexes rather than their constituent subunits. We explore how substrate multimerization modulates recognition by the ClpX unfoldase using a natural substrate, MuA t...

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Detalhes bibliográficos
Main Authors: Abdelhakim, Aliaa H., Oakes, Elizabeth C., Sauer, Robert T., Baker, Tania A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717000/
https://ncbi.nlm.nih.gov/pubmed/18406325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.02.013
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