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Deciphering the roles of multi-component recognition signals by the AAA+ unfoldase, ClpX

ATP-dependent protein remodeling and unfolding enzymes are key participants in protein metabolism in all cells. How these often-destructive enzymes specifically recognize target protein complexes is poorly understood. Here, we use the well-studied AAA+ unfoldase-substrate pair, E. coli ClpX and MuA...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Ling, Lorraine, Montaño, Sherwin P., Sauer, Robert T., Rice, Phoebe A., Baker, Tania A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569521/
https://ncbi.nlm.nih.gov/pubmed/25797169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.03.008
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