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Role of the processing pore of the ClpX AAA+ ATPase in the recognition and engagement of specific protein substrates
ClpX binds substrates bearing specific classes of peptide signals, denatures these proteins, and translocates them through a central pore into ClpP for degradation. ClpX with the V154F pore mutation is severely defective in binding substrates bearing C-motif 1 degradation signals and is also impaire...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC359390/ https://ncbi.nlm.nih.gov/pubmed/15004005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1170304 |
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