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Mechanistic insights into bacterial AAA+ proteases and protein-remodelling machines

To maintain protein homeostasis, AAA+ proteolytic machines degrade damaged and unneeded proteins in bacteria, archaea and eukaryotes. This process involves ATP-dependent unfolding of a target protein and subsequent translocation into a self-compartmentalized proteolytic chamber. Related AAA+ enzymes...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Rev Microbiol
Prif Awduron: Olivares, Adrian O., Baker, Tania A., Sauer, Robert T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458636/
https://ncbi.nlm.nih.gov/pubmed/26639779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrmicro.2015.4
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