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Dissection of axial-pore loop function during unfolding and translocation by a AAA+ proteolytic machine
In the axial channels of ClpX and related hexameric AAA+ protein-remodeling rings, the pore-1 loops are thought to play important roles in engaging, mechanically unfolding, and translocating protein substrates. How these loops perform these functions and whether they also prevent substrate dissociat...
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| Publicado en: | Cell Rep |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4536184/ https://ncbi.nlm.nih.gov/pubmed/26235618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.07.007 |
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