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Coordinated gripping of substrate by subunits of a AAA+ proteolytic machine
Hexameric AAA+ unfoldases of ATP-dependent proteases and protein-remodeling machines use conserved loops that line the axial pore to apply force to substrates during the mechanical processes of protein unfolding and translocation. Whether loops from multiple subunits act independently or coordinatel...
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| Publicado no: | Nat Chem Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4333055/ https://ncbi.nlm.nih.gov/pubmed/25599533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1732 |
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