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Polypeptide translocation by the AAA+ ClpXP protease machine
In the AAA+ ClpXP protease, ClpX uses repeated cycles of ATP hydrolysis to pull native proteins apart and to translocate the denatured polypeptide into ClpP for degradation. Here, we probe polypeptide features important for translocation. ClpXP degrades diverse synthetic peptide substrates despite m...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2718738/ https://ncbi.nlm.nih.gov/pubmed/19549599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2009.05.007 |
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