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Polypeptide translocation by the AAA+ ClpXP protease machine

In the AAA+ ClpXP protease, ClpX uses repeated cycles of ATP hydrolysis to pull native proteins apart and to translocate the denatured polypeptide into ClpP for degradation. Here, we probe polypeptide features important for translocation. ClpXP degrades diverse synthetic peptide substrates despite m...

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書誌詳細
主要な著者: Barkow, Sarah R., Levchenko, Igor, Baker, Tania A., Sauer, Robert T.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718738/
https://ncbi.nlm.nih.gov/pubmed/19549599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2009.05.007
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