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Polypeptide translocation by the AAA+ ClpXP protease machine

In the AAA+ ClpXP protease, ClpX uses repeated cycles of ATP hydrolysis to pull native proteins apart and to translocate the denatured polypeptide into ClpP for degradation. Here, we probe polypeptide features important for translocation. ClpXP degrades diverse synthetic peptide substrates despite m...

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Bibliografische gegevens
Hoofdauteurs: Barkow, Sarah R., Levchenko, Igor, Baker, Tania A., Sauer, Robert T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718738/
https://ncbi.nlm.nih.gov/pubmed/19549599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2009.05.007
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