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Multistep substrate binding and engagement by the AAA+ ClpXP protease
Escherichia coli ClpXP is one of the most thoroughly studied AAA+ proteases, but relatively little is known about the reactions that allow it to bind and then engage specific protein substrates before the adenosine triphosphate (ATP)-fueled mechanical unfolding and translocation steps that lead to p...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7668067/ https://ncbi.nlm.nih.gov/pubmed/33106413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2010804117 |
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