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Loop Dynamics and Enzyme Catalysis in Protein Tyrosine Phosphatases
[Image: see text] Protein tyrosine phosphatases (PTPs) play an important role in cellular signaling and have been implicated in human cancers, diabetes, and obesity. Despite shared catalytic mechanisms and transition states for the chemical steps of catalysis, catalytic rates within the PTP family v...
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| 出版年: | J Am Chem Soc |
|---|---|
| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical
Society
2021
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8031367/ https://ncbi.nlm.nih.gov/pubmed/33661624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c11806 |
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