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Dynamics of the WPD Loop of the Yersinia Protein Tyrosine Phosphatase

The bacterial protein tyrosine phosphatase YopH is an essential virulence determinant in Yersinia spp., causing gastrointestinal diseases and the plague. Like eukaryotic PTPases, YopH catalyzes the hydrolysis of the phosphate moiety of phosphotyrosine within a highly conserved binding pocket, which...

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Detalles Bibliográficos
Main Authors: Hu, Xin, Stebbins, C. Erec
Formato: Artigo
Idioma:Inglês
Publicado: Biophysical Society 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563744/
https://ncbi.nlm.nih.gov/pubmed/16698773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.080259
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