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Dynamics of the WPD Loop of the Yersinia Protein Tyrosine Phosphatase

The bacterial protein tyrosine phosphatase YopH is an essential virulence determinant in Yersinia spp., causing gastrointestinal diseases and the plague. Like eukaryotic PTPases, YopH catalyzes the hydrolysis of the phosphate moiety of phosphotyrosine within a highly conserved binding pocket, which...

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Bibliografiske detaljer
Main Authors: Hu, Xin, Stebbins, C. Erec
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563744/
https://ncbi.nlm.nih.gov/pubmed/16698773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.080259
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