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Dynamics of the WPD Loop of the Yersinia Protein Tyrosine Phosphatase

The bacterial protein tyrosine phosphatase YopH is an essential virulence determinant in Yersinia spp., causing gastrointestinal diseases and the plague. Like eukaryotic PTPases, YopH catalyzes the hydrolysis of the phosphate moiety of phosphotyrosine within a highly conserved binding pocket, which...

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Autors principals: Hu, Xin, Stebbins, C. Erec
Format: Artigo
Idioma:Inglês
Publicat: Biophysical Society 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563744/
https://ncbi.nlm.nih.gov/pubmed/16698773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.080259
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