mTOR-driven neural circuit changes initiate an epileptogenic cascade

Mutations in genes regulating mTOR pathway signaling are now recognized as a significant cause of epilepsy. Interestingly, these mTORopathies are often caused by somatic mutations, affecting variable numbers of neurons. To better understand how this variability affects disease phenotype, we develope...

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Detaylı Bibliyografya
Yayımlandı:Prog Neurobiol
Asıl Yazarlar: LaSarge, Candi L., Pun, Raymund Y.K., Gu, Zhiqing, Riccetti, Matthew R., Namboodiri, Devi V., Tiwari, Durgesh, Gross, Christina, Danzer, Steve C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026598/
https://ncbi.nlm.nih.gov/pubmed/33309800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pneurobio.2020.101974
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