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mTOR-driven neural circuit changes initiate an epileptogenic cascade

Mutations in genes regulating mTOR pathway signaling are now recognized as a significant cause of epilepsy. Interestingly, these mTORopathies are often caused by somatic mutations, affecting variable numbers of neurons. To better understand how this variability affects disease phenotype, we develope...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Prog Neurobiol
मुख्य लेखकों: LaSarge, Candi L., Pun, Raymund Y.K., Gu, Zhiqing, Riccetti, Matthew R., Namboodiri, Devi V., Tiwari, Durgesh, Gross, Christina, Danzer, Steve C.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026598/
https://ncbi.nlm.nih.gov/pubmed/33309800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pneurobio.2020.101974
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