mTOR-driven neural circuit changes initiate an epileptogenic cascade

Mutations in genes regulating mTOR pathway signaling are now recognized as a significant cause of epilepsy. Interestingly, these mTORopathies are often caused by somatic mutations, affecting variable numbers of neurons. To better understand how this variability affects disease phenotype, we develope...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Prog Neurobiol
Hauptverfasser: LaSarge, Candi L., Pun, Raymund Y.K., Gu, Zhiqing, Riccetti, Matthew R., Namboodiri, Devi V., Tiwari, Durgesh, Gross, Christina, Danzer, Steve C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026598/
https://ncbi.nlm.nih.gov/pubmed/33309800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pneurobio.2020.101974
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge