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mTOR-driven neural circuit changes initiate an epileptogenic cascade
Mutations in genes regulating mTOR pathway signaling are now recognized as a significant cause of epilepsy. Interestingly, these mTORopathies are often caused by somatic mutations, affecting variable numbers of neurons. To better understand how this variability affects disease phenotype, we develope...
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| Publié dans: | Prog Neurobiol |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8026598/ https://ncbi.nlm.nih.gov/pubmed/33309800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pneurobio.2020.101974 |
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