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Impact of mTOR hyperactive neurons on the morphology and physiology of adjacent neurons: Do PTEN KO cells make bad neighbors?

Hyperactivation of the mechanistic target of rapamycin (mTOR) pathway is associated with epilepsy, autism and brain growth abnormalities in humans. mTOR hyperactivation often results from developmental somatic mutations, producing genetic lesions and associated dysfunction in relatively restricted p...

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Publicat a:Exp Neurol
Autors principals: LaSarge, Candi L., Pun, Raymund Y.K., Gu, Zhiqing, Santos, Victor R., Danzer, Steve C.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744293/
https://ncbi.nlm.nih.gov/pubmed/31377403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2019.113029
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