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PTEN deletion increases hippocampal granule cell excitability in male and female mice
Deletion of the mTOR pathway inhibitor PTEN from postnatally-generated hippocampal dentate granule cells causes epilepsy. Here, we conducted field potential, whole cell recording and single cell morphology studies to begin to elucidate the mechanisms by which granule cell-specific PTEN-loss produces...
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| Publicado no: | Neurobiol Dis |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5675774/ https://ncbi.nlm.nih.gov/pubmed/28855130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.08.014 |
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