Defective Phosphoinositide Metabolism in Autism

Por Gross, Christina
Publicado no J Neurosci Res (2016)

Excess Protein Synthesis in FXS Patient Lymphoblastoid Cells Can Be Rescued with a p110β-Selective Inhibitor

Por Gross, Christina, Bassell, Gary J
Publicado em 2011

Neuron-specific regulation of class I PI3K catalytic subunits and their dysfunction in brain disorders

Por Gross, Christina, Bassell, Gary J.
Publicado em 2014

Therapeutic Strategies in Fragile X Syndrome: Dysregulated mGluR Signaling and Beyond

Por Gross, Christina, Berry-Kravis, Elizabeth M, Bassell, Gary J
Publicado em 2012

Automated 4D analysis of dendritic spine morphology: applications to stimulus-induced spine remodeling and pharmacological rescue in a disease model

Por Swanger, Sharon A, Yao, Xiaodi, Gross, Christina, Bassell, Gary J
Publicado em 2011

Dephosphorylation-Induced Ubiquitination and Degradation of FMRP in Dendrites: A Role in Immediate Early mGluR-Stimulated Translation

Por Nalavadi, Vijayalaxmi C., Muddashetty, Ravi S., Gross, Christina, Bassell, Gary J.
Publicado em 2012

Identification of Axon-Enriched MicroRNAs Localized to Growth Cones of Cortical Neurons

Por Sasaki, Yukio, Gross, Christina, Xing, Lei, Goshima, Yoshio, Bassell, Gary J.
Publicado em 2013

Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and Back

Por Gross, Christina, Hoffmann, Anne, Bassell, Gary J., Berry-Kravis, Elizabeth M.
Publicado no Neurotherapeutics (2015)

Fragile X Mental Retardation Protein Regulates Protein Expression and mRNA Translation of the Potassium Channel Kv4.2

Por Gross, Christina, Yao, Xiaodi, Pong, Dan L., Jeromin, Andreas, Bassell, Gary J.
Publicado em 2011

Increased expression of the PI3K catalytic subunit p110δ underlies elevated S6 phosphorylation and protein synthesis in an individual with autism from a multiplex family

Por Poopal, Ashwini C., Schroeder, Lindsay M., Horn, Paul S., Bassell, Gary J., Gross, Christina
Publicado no Mol Autism (2016)

Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation and mGluR signaling

Por Muddashetty, Ravi S., Nalavadi, Vijayalaxmi C., Gross, Christina, Yao, Xiaodi, Xing, Lei, Laur, Oskar, Warren, Stephen T., Bassell, Gary J.
Publicado em 2011

Excess Phosphoinositide 3-Kinase Subunit Synthesis and Activity as a Novel Therapeutic Target in Fragile X Syndrome

Por Gross, Christina, Nakamoto, Mika, Yao, Xiaodi, Chan, Chi-Bun, Yim, So Y., Ye, Keqiang, Warren, Stephen T., Bassell, Gary J.
Publicado em 2010

Arc/Arg3.1 mRNA expression reveals a sub-cellular trace of prior sound exposure in adult primary auditory cortex

Por Ivanova, Tamara, Matthews, Andrew, Gross, Christina, Mappus, Rudolph C., Gollnick, Clare, Swanson, Andrew, Bassell, Gary J., Liu, Robert C.
Publicado em 2011

Dysregulation of mRNA Localization and Translation in Genetic Disease

Por Wang, Eric T., Taliaferro, J. Matthew, Lee, Ji-Ann, Sudhakaran, Indulekha P., Rossoll, Wilfried, Gross, Christina, Moss, Kathryn R., Bassell, Gary J.
Publicado no J Neurosci (2016)

Selective role of the catalytic PI3K subunit p110β in impaired higher-order cognition in Fragile X syndrome

Por Gross, Christina, Raj, Nisha, Molinaro, Gemma, Allen, Amanda G., Whyte, Alonzo J., Gibson, Jay R., Huber, Kimberly M., Gourley, Shannon L., Bassell, Gary J.
Publicado no Cell Rep (2015)

Experience-induced Arc/Arg3.1 primes CA1 pyramidal neurons for mGluR-dependent long-term synaptic depression

Por Jakkamstti, Vikam, Tsai, Nien-Pei, Gross, Christina, Molinaro, Gemma, Collins, Katie A., Nicoletti, Ferdinando, Wang, Kuan H., Osten, Pavel, Bassell, Gary J., Gibson, Jay R., Huber, Kimberly M.
Publicado em 2013

MeCP2 Regulates the Synaptic Expression of a Dysbindin-BLOC-1 Network Component in Mouse Brain and Human Induced Pluripotent Stem Cell-Derived Neurons

Por Larimore, Jennifer, Ryder, Pearl V., Kim, Kun-Yong, Ambrose, L. Alex, Chapleau, Christopher, Calfa, Gaston, Gross, Christina, Bassell, Gary J., Pozzo-Miller, Lucas, Smith, Yoland, Talbot, Konrad, Park, In-Hyun, Faundez, Victor
Publicado em 2013

MicroRNA-mediated downregulation of the potassium channel Kv4.2 contributes to seizure onset

Por Gross, Christina, Yao, Xiaodi, Engel, Tobias, Tiwari, Durgesh, Xing, Lei, Rowley, Shane, Danielson, Scott Walter, Thomas, Kristen Therese, Jimenez-Mateos, Eva Maria, Schroeder, Lindsay Michelle, Pun, Raymund Yu Kwan, Danzer, Steve Craig, Henshall, David Clifford, Bassell, Gary Jonathan
Publicado no Cell Rep (2016)

Increased expression of the PI3K enhancer PIKE mediates deficits in synaptic plasticity and behavior in Fragile X syndrome

Por Gross, Christina, Chang, Chia-Wei, Kelly, Seth M., Bhattacharya, Aditi, McBride, Sean M.J., Danielson, Scott W., Jiang, Michael Q., Chan, Chi Bun, Ye, Keqiang, Gibson, Jay R., Klann, Eric, Jongens, Thomas A., Moberg, Kenneth H., Huber, Kimberly M., Bassell, Gary J.
Publicado no Cell Rep (2015)

Mutation of the conserved polyadenosine RNA binding protein, ZC3H14/dNab2, impairs neural function in Drosophila and humans

Por Pak, ChangHui, Garshasbi, Masoud, Kahrizi, Kimia, Gross, Christina, Apponi, Luciano H., Noto, John J., Kelly, Seth M., Leung, Sara W., Tzschach, Andreas, Behjati, Farkhondeh, Abedini, Seyedeh Sedigheh, Mohseni, Marzieh, Jensen, Lars R., Hu, Hao, Huang, Brenda, Stahley, Sara N., Liu, Guanglu, Williams, Kathryn R., Burdick, Sharon, Feng, Yue, Sanyal, Subhabrata, Bassell, Gary J., Ropers, Hans-Hilger, Najmabadi, Hossein, Corbett, Anita H., Moberg, Kenneth H., Kuss, Andreas W.
Publicado em 2011