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MicroRNA-mediated downregulation of the potassium channel Kv4.2 contributes to seizure onset
Seizures are bursts of excessive synchronized neuronal activity, suggesting that mechanisms controlling brain excitability are compromised. The voltage-gated potassium channel Kv4.2, a major mediator of hyperpolarizing A-type currents in the brain, is a crucial regulator of neuronal excitability. Kv...
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| izdano v: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5061042/ https://ncbi.nlm.nih.gov/pubmed/27681419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.08.074 |
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