Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation and mGluR signaling

The molecular mechanism how RISC and microRNAs selectively and reversibly regulate mRNA translation in response to receptor signaling is unknown but could provide a means for temporal and spatial control of translation. Here we show that miR-125a targeting PSD-95 mRNA allows reversible inhibition of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Muddashetty, Ravi S., Nalavadi, Vijayalaxmi C., Gross, Christina, Yao, Xiaodi, Xing, Lei, Laur, Oskar, Warren, Stephen T., Bassell, Gary J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115785/
https://ncbi.nlm.nih.gov/pubmed/21658607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.05.006
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