FMRP Phosphorylation Reveals an Immediate-Early Signaling Pathway Triggered by Group I mGluR and Mediated by PP2A

Eitemau Tebyg

• S6K1 Phosphorylates and Regulates Fragile X Mental Retardation Protein (FMRP) with the Neuronal Protein Synthesis-dependent Mammalian Target of Rapamycin (mTOR) Signaling Cascade
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• Dephosphorylation-Induced Ubiquitination and Degradation of FMRP in Dendrites: A Role in Immediate Early mGluR-Stimulated Translation
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• Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors
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  Cyhoeddwyd: (2007)
• Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation and mGluR signaling
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  Cyhoeddwyd: (2011)
• Phosphorylation of FMRP inhibits association with Dicer
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  Cyhoeddwyd: (2009)