FMRP Phosphorylation Reveals an Immediate-Early Signaling Pathway Triggered by Group I mGluR and Mediated by PP2A

Fragile X syndrome is a common form of inherited mental retardation and is caused by loss of fragile X mental retardation protein (FMRP), a selective RNA-binding protein that influences the translation of target messages. Here, we identify protein phosphatase 2A (PP2A) as an FMRP phosphatase and rep...

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Vydáno v:J Neurosci
Hlavní autoři: Narayanan, Usha, Nalavadi, Vijayalaxmi, Nakamoto, Mika, Pallas, David C., Ceman, Stephanie, Bassell, Gary J., Warren, Stephen T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673448/
https://ncbi.nlm.nih.gov/pubmed/18160642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2969-07.2007
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