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Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors
Fragile X syndrome (FXS), a common inherited form of mental retardation, is caused by the functional absence of the fragile X mental retardation protein (FMRP), an RNA-binding protein that regulates the translation of specific mRNAs at synapses. Altered synaptic plasticity has been described in a mo...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2000537/ https://ncbi.nlm.nih.gov/pubmed/17881561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707484104 |
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