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Therapeutic Strategies in Fragile X Syndrome: Dysregulated mGluR Signaling and Beyond
Fragile X syndrome (FXS) is an inherited neurodevelopmental disease caused by loss of function of the fragile X mental retardation protein (FMRP). In the absence of FMRP, signaling through group 1 metabotropic glutamate receptors is elevated and insensitive to stimulation, which may underlie many of...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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Nature Publishing Group
2012
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3238060/ https://ncbi.nlm.nih.gov/pubmed/21796106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.137 |
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