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Therapeutic Strategies in Fragile X Syndrome: Dysregulated mGluR Signaling and Beyond
Fragile X syndrome (FXS) is an inherited neurodevelopmental disease caused by loss of function of the fragile X mental retardation protein (FMRP). In the absence of FMRP, signaling through group 1 metabotropic glutamate receptors is elevated and insensitive to stimulation, which may underlie many of...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3238060/ https://ncbi.nlm.nih.gov/pubmed/21796106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.137 |
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