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Selectivity via Cooperativity: Preferential Stabilization of the p65/14-3-3 Interaction with Semisynthetic Natural Products
[Image: see text] Natural compounds are an important class of potent drug molecules including some retrospectively found to act as stabilizers of protein–protein interactions (PPIs). However, the design of synthetic PPI stabilizers remains an understudied approach. To date, there are limited example...
সংরক্ষণ করুন:
| প্রকাশিত: | J Am Chem Soc |
|---|---|
| প্রধান লেখক: | , , , , , , , , , |
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
American Chemical
Society
2020
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| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8022324/ https://ncbi.nlm.nih.gov/pubmed/32501683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c02151 |
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