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A Thermodynamic Model for Multivalency in 14-3-3 Protein–Protein Interactions

[Image: see text] Protein–protein interactions (PPIs) are at the core of molecular control over cellular function. Multivalency in PPI formation, such as via proteins with multiple binding sites and different valencies, requires fundamental understanding to address correlated challenges in pathologi...

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Podrobná bibliografie
Vydáno v:J Am Chem Soc
Hlavní autoři: Stevers, Loes M., de Vink, Pim J., Ottmann, Christian, Huskens, Jurriaan, Brunsveld, Luc
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2018
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6213025/
https://ncbi.nlm.nih.gov/pubmed/30296824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b09618
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