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Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions
[Image: see text] The stabilization of protein complexes has emerged as a promising modality, expanding the number of entry points for novel therapeutic intervention. Targeting proteins that mediate protein–protein interactions (PPIs), such as hub proteins, is equally challenging and rewarding as th...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J Am Chem Soc |
|---|---|
| Prif Awduron: | , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Chemical
Society
2021
|
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8193639/ https://ncbi.nlm.nih.gov/pubmed/34047554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.1c03035 |
| Tagiau: |
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