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Cooperativity between the orthosteric and allosteric ligand binding sites of RORγt
Cooperative ligand binding is an important phenomenon in biological systems where ligand binding influences the binding of another ligand at an alternative site of the protein via an intramolecular network of interactions. The underlying mechanisms behind cooperative binding remain poorly understood...
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| Опубликовано в: : | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8017705/ https://ncbi.nlm.nih.gov/pubmed/33536342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2021287118 |
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