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Ligand-Based Design of Allosteric Retinoic Acid Receptor-Related Orphan Receptor γt (RORγt) Inverse Agonists
[Image: see text] Retinoic acid receptor-related orphan receptor γt (RORγt) is a nuclear receptor associated with the pathogenesis of autoimmune diseases. Allosteric inhibition of RORγt is conceptually new, unique for this specific nuclear receptor, and offers advantages over traditional orthosteric...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Med Chem |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Chemical
Society
2019
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| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6956242/ https://ncbi.nlm.nih.gov/pubmed/31821760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.9b01372 |
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