Cooperativity between the orthosteric and allosteric ligand binding sites of RORγt

Cooperative ligand binding is an important phenomenon in biological systems where ligand binding influences the binding of another ligand at an alternative site of the protein via an intramolecular network of interactions. The underlying mechanisms behind cooperative binding remain poorly understood...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: de Vries, Rens M. J. M., Meijer, Femke A., Doveston, Richard G., Leijten-van de Gevel, Iris A., Brunsveld, Luc
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2021
Konular:
Physical Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017705/
https://ncbi.nlm.nih.gov/pubmed/33536342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2021287118
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