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Type II Binders Targeting the “GLR-out” Conformation of the Pseudokinase STRADα
Pseudokinases play important roles in signal transduction and cellular processes similarly to catalytically competent kinases. However, pseudokinase pharmacological tractability and conformational space accessibility are poorly understood. Pseudokinases have only recently been suggested to adopt “in...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7995334/ https://ncbi.nlm.nih.gov/pubmed/33440120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00714 |
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