STRAD pseudokinases regulate axogenesis and LKB1 stability

BACKGROUND: Neuronal polarization is an essential step of morphogenesis and connectivity in the developing brain. The serine/threonine kinase LKB1 is a key regulator of cell polarity, metabolism, tumorigenesis, and is required for axon formation. It is allosterically regulated by two related and evo...

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Hauptverfasser: Veleva-Rotse, Biliana O, Smart, James L, Baas, Annette F, Edmonds, Benjamin, Zhao, Zi-ming, Brown, Allyson, Klug, Lillian R, Hansen, Kelly, Reilly, Gabrielle, Gardner, Alexandria P, Subbiah, Krishnaveni, Gaucher, Eric A, Clevers, Hans, Barnes, Anthony P
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016016/
https://ncbi.nlm.nih.gov/pubmed/24594058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8104-9-5
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