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STRAD pseudokinases regulate axogenesis and LKB1 stability
BACKGROUND: Neuronal polarization is an essential step of morphogenesis and connectivity in the developing brain. The serine/threonine kinase LKB1 is a key regulator of cell polarity, metabolism, tumorigenesis, and is required for axon formation. It is allosterically regulated by two related and evo...
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主要な著者: | , , , , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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BioMed Central
2014
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4016016/ https://ncbi.nlm.nih.gov/pubmed/24594058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8104-9-5 |
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