Metabolic support of tumor-infiltrating regulatory T cells by lactic acid

Regulatory T (T(reg)) cells, vital for maintaining immune homeostasis, also represent a major barrier to cancer immunity, as the tumor microenvironment (TME) promotes T(reg) cell recruitment, differentiation, and activity(1,2). Tumor cells have deregulated metabolism leading to a metabolite-depleted...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nature
Autors principals: Watson, McLane J., Vignali, Paolo D.A., Mullett, Steven J., Overacre-Delgoffe, Abigail E., Peralta, Ronal M., Grebinoski, Stephanie, Menk, Ashley V., Rittenhouse, Natalie L., DePeaux, Kristin, Whetstone, Ryan D., Vignali, Dario A. A., Hand, Timothy W., Poholek, Amanda C., Morrison, Brett M., Rothstein, Jeffrey D., Wendell, Stacy G., Delgoffe, Greg M.
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990682/
https://ncbi.nlm.nih.gov/pubmed/33589820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-03045-2
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars