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T(REG) FRAGILITY: A PREREQUISITE FOR EFFECTIVE ANTITUMOR IMMUNITY?

Inhibitory checkpoint blockade has significantly improved patient response rate across numerous tumor types. However, most patients remain unresponsive to immunotherapy, suggesting that unappreciated mechanisms of resistance exist. The tumor microenvironment (TME) is unique and comprised of many sup...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Overacre-Delgoffe, Abigail E., Vignali, Dario A.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080214/
https://ncbi.nlm.nih.gov/pubmed/30068755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0066
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