Metabolic support of tumor-infiltrating regulatory T cells by lactic acid

Regulatory T (T(reg)) cells, vital for maintaining immune homeostasis, also represent a major barrier to cancer immunity, as the tumor microenvironment (TME) promotes T(reg) cell recruitment, differentiation, and activity(1,2). Tumor cells have deregulated metabolism leading to a metabolite-depleted...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Nature
Asıl Yazarlar: Watson, McLane J., Vignali, Paolo D.A., Mullett, Steven J., Overacre-Delgoffe, Abigail E., Peralta, Ronal M., Grebinoski, Stephanie, Menk, Ashley V., Rittenhouse, Natalie L., DePeaux, Kristin, Whetstone, Ryan D., Vignali, Dario A. A., Hand, Timothy W., Poholek, Amanda C., Morrison, Brett M., Rothstein, Jeffrey D., Wendell, Stacy G., Delgoffe, Greg M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990682/
https://ncbi.nlm.nih.gov/pubmed/33589820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-03045-2
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller